Tested on Arch Linux with Nvidia proprietary drivers (396.54.09), Wine Staging 3.19 (esync) and DXVK (963bd66). Recorded at 1080p with OBS (NVENC).
I have installed DirectX End-User Runtimes (June 2010) + XACT, through winetricks or importing in your wineprefix regedit the .reg file below in the description.
Framerate can be unlocked with the boolean “iPresentInterval=0” under the [Display] tab, in “Fallout4Pref.ini” (located in “~/Documents/My Games/Fallout4”).
“Crazy mouse” bug, can be fixed with the boolean “bBackgroundMouse=1” under the [Controls] tab, in “Fallout4_Default.ini” (located in the game main folder) and (eventually) in “Fallout4.ini” (located in “~/Documents/My Games/Fallout4”).
“Invisible mouse pointer” bug, can be fixed with the boolean “bGamepadEnable=0” under the [General] tab, in “Fallout4_Default.ini” (located in “~/Documents/My Games/Fallout4”).
“Audio cuts out” bug, requires a patch (link below in the description).
Gaining 5-10 FPS without OBS recording, 10(ish) more FPS with FXAA instead of TAA and advanced settings on low-medium.
Fallout 4 Sound Patch:
xact.tar.xz (.reg file):
CPU: AMD Ryzen 3 2200G 3.5GHz
Mobo: Gigabyte GA-AB350M-DS3H
RAM: 16GB DDR4 2666 MT/s Crucial
GC: Nvidia GeForce GTX 1060 3GB DDR5
Case: Inter-Tech Tower Q2 Illuminator
PSU: Silent 500W LC-Power